On January 18, 1824, the first Jewish congregation in Cincinnati was formed, the first west of New York, making the Queen City a center of Judaism in the United States.

The first recorded Jewish man in Cincinnati was Joseph Jonas, a watchmaker, from Plymouth in England, who arrived in New York in October 1816 with the intent of making his way to the new city of Cincinnati. He left for Cincinnati from Philadelphia on January 2 in 1817 but did not arrive in Cincinnati until March 8, two months later, after a long and difficult journey traveling in horse carriage across the mountains and then on a flatboat (see below) south on the Ohio River.